Chilean biotech company Sticta Biologicals and cultivated meat company Meatable have received a Good Food Institute research grant to create a detailed model of pig cells.

Along with Merken Biotech and the Center for Mathematical Modeling at the University of Chile, the aim of the research project is to develop a precise and genome-scale metabolic model of porcine cells.

This model will help to identify the most efficient way to feed porcine cells and ultimately increase yield, aiming to make cell-based pork more efficient and scalable.

The precise and robust proteome-constrained genome-scale metabolic model of porcine cells will be refined and validated using -omics experimental data obtained from time-course studies of the expansion and proliferation phases of pork cell lines provided by Meatable.

The model will boost understanding of why cell biology changes during proliferation and will aid in media and cell line improvements that allow for longer expansion phases at faster population doublings, increasing yield and reducing process variability.

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